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Nei pazienti che ricevono medicinali antipertensivi concomitanti, il tadalafil può indurre una riduzione della pressione del sangue.

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Disturbi della vista e casi di NAION sono stati segnalati in associazione all’uso di tadalafil ed altri inibitori della PDE5. Le analisi dei dati osservazionali suggeriscono un aumentato rischio di NAION acuta in uomini con disfunzione erettile dopo esposizione a tadalafil o altri inibitori della PDE5.

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